Cardiac and coronary function in the Langendorff-perfused mouse heart model
نویسندگان
چکیده
منابع مشابه
Dynasore Protects Mitochondria and Improves Cardiac Lusitropy in Langendorff Perfused Mouse Heart
BACKGROUND Heart failure due to diastolic dysfunction exacts a major economic, morbidity and mortality burden in the United States. Therapeutic agents to improve diastolic dysfunction are limited. It was recently found that Dynamin related protein 1 (Drp1) mediates mitochondrial fission during ischemia/reperfusion (I/R) injury, whereas inhibition of Drp1 decreases myocardial infarct size. We hy...
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ژورنال
عنوان ژورنال: Experimental Physiology
سال: 2008
ISSN: 0958-0670
DOI: 10.1113/expphysiol.2008.043554